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Siemens Healthcare Diagnostics, Inc.
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For patients in need of an early diagnosis, a rapidly appearing biochemical marker (such as Myoglobin) plus a specific marker that rises later (e.g., cTnI) are recommended.1 In addition, Myoglobin has an excellent negative predictive value in the evaluation of patients with acute chest pain.2-6
Myoglobin, a low molecular weight heme protein found in cardiac and skeletal muscle, is valuable in the early evaluation of chest pain patients. It may appear in the blood in abnormal levels as early as 1 to 3 hours after onset of myocardial ischemia. While Myoglobin is not specific to cardiac muscle,
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